Menopause hormone replacement therapy

Menopause is best characterized by which of the following sets of hormonal changes?

1: Low estrogen and low follicle-stimulating hormone (FSH) levels
2: Low estrogen and high follicle-stimulating hormone (FSH) levels
3: High estrogen and low follicle-stimulating hormone (FSH) levels
4: High estrogen and high follicle-stimulating hormone (FSH) levels